Gypenoside XVII
Gypenoside XVII (Gynosaponin S) is a neuroprotective agent that counteracts Aβ25-35-induced toxicity by activating estrogen receptor-dependent PI3K/Akt and Nrf2/HO-1 pathways while inhibiting GSK-3β. This small molecule is used in research on Alzheimer's disease models, demonstrating protective effects in both cellular and animal studies.
Product Specifications
CAS Number
80321-69-3
Product Name Alternative
EndogenousMetabolite, Endogenous Metabolite, Inhibitor, Gynosaponin S, Gypenoside XVII, GSK3, EstrogenReceptor, Estrogen Receptor/ERR, GSK-3β, Estrogen Receptor, GP17, GP-17, GP 17, ERR, inhibit
Field of Research
Metabolism Research, Signal Transduction, Stem Cell & Developmental Biology
Purity
98.00% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (2.11 mM) ; DMSO:60 mg/mL (63.35 mM)
Smiles
C\C (C) =C\CC[C@] (C) (O[C@@H]1O[C@H] (CO[C@@H]2O[C@H] (CO) [C@@H] (O) [C@H] (O) [C@H]2O) [C@@H] (O) [C@H] (O) [C@H]1O) [C@H]1CC[C@]2 (C) C1[C@H] (O) CC1[C@@]3 (C) CC[C@H] (O[C@@H]4O[C@H] (CO) [C@@H] (O) [C@H] (O) [C@H]4O) C (C) (C) C3CC[C@@]21C
Molecular Formula
C48H82O18
Molecular Weight
947.15
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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