SKLB4771
SKLB4771 (FLT3-IN-1) is a potent and selective inhibitor of FMS-like tyrosine kinase 3 (FLT3) . It is a valuable research tool for investigating FLT3-driven mechanisms in acute myeloid leukemia (AML), supporting both in vitro cellular assays and in vivo preclinical studies.
Product Specifications
CAS Number
1370256-78-2
Product Name Alternative
Phosphorylation, selective, SKLB 4771, SKLB4771, SKLB-4771, SCFR, inhibit, FLT3, FLT3-IN-1, FLT3-IN-1, Fms like tyrosine kinase 3, Inhibitor, apoptosis induction, cell proliferation inhibition, c-Kit, Cluster of differentiation antigen 135, CD135, CD117
Field of Research
Cardiovascular Research, Cell Biology, Signal Transduction
Purity
98.00% (May vary between batches)
Solubility
DMSO:50 mg/mL (93 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (3.72 mM)
Smiles
Cc1ccc (NC (=O) Nc2nnc (Sc3ncnc4cc (OCCCN5CCOCC5) ccc34) s2) cc1
Molecular Formula
C25H27N7O3S2
Molecular Weight
537.66
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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