ADX-47273
ADX-47273 is a selective positive allosteric modulator of the mGluR5 receptor with an EC50 of 170 nM. This compound is a valuable research tool for investigating mGluR5 function in models of CNS disorders, including in vitro assays and in vivo behavioral studies.
Product Specifications
CAS Number
851881-60-2
Product Name Alternative
ADX 47273, ADX47273, ADX-47273, BA94673139, BA-94673139, BA 94673139, antipsychotic, inhibit, Inhibitor, mGluR, mGluR5, Metabotropic glutamate receptors, glutamate, procognitive
Field of Research
Metabolism Research, Neuroscience
Purity
97.00% (May vary between batches)
Solubility
DMSO:69 mg/mL (186.81 mM) ; H2O:< 1 mg/mL (insoluble or slightly soluble) ; Ethanol:28 mg/mL (75.81 mM) ;10% DMSO+90% Corn Oil:2.5 mg/mL (6.77 mM)
Smiles
Fc1ccc (cc1) C (=O) N1CCC[C@@H] (C1) c1nc (no1) -c1ccc (F) cc1
Molecular Formula
C20H17F2N3O2
Molecular Weight
369.36
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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