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ELR510444

ELR510444 is a potent novel microtubule-disrupting agent that inhibits the proliferation of MDA-MB-231 breast cancer cells with an IC50 of 30.9 nM. It is not a P-glycoprotein substrate and remains effective against cells overexpressing βIII-tubulin, making it a valuable research tool for studying multidrug-resistant cancers in vitro.

Product Specifications

CAS Number

1233948-35-0

Product Name Alternative

Apoptosis, inhibit, LR510444, LR 510444, LR-510444, MicrotubuleAssociated, Microtubule Associated, Microtubule/Tubulin, Microtubule disruptor, ELR 510444, ELR510444, ELR-510444, Inhibitor

Field of Research

Cell Biology, Signal Transduction

Purity

97.67% (May vary between batches)

Solubility

DMSO:50 mg/mL (135.7 mM)

Smiles

Cc1ccc (cc1) S (=O) (=O) Nc1cc (ccc1C) -c1ccc (s1) C#N

Molecular Formula

C19H16N2O2S2

Molecular Weight

368.47

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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