ELR510444
ELR510444 is a potent novel microtubule-disrupting agent that inhibits the proliferation of MDA-MB-231 breast cancer cells with an IC50 of 30.9 nM. It is not a P-glycoprotein substrate and remains effective against cells overexpressing βIII-tubulin, making it a valuable research tool for studying multidrug-resistant cancers in vitro.
Product Specifications
CAS Number
1233948-35-0
Product Name Alternative
Apoptosis, inhibit, LR510444, LR 510444, LR-510444, MicrotubuleAssociated, Microtubule Associated, Microtubule/Tubulin, Microtubule disruptor, ELR 510444, ELR510444, ELR-510444, Inhibitor
Field of Research
Cell Biology, Signal Transduction
Purity
97.67% (May vary between batches)
Solubility
DMSO:50 mg/mL (135.7 mM)
Smiles
Cc1ccc (cc1) S (=O) (=O) Nc1cc (ccc1C) -c1ccc (s1) C#N
Molecular Formula
C19H16N2O2S2
Molecular Weight
368.47
Storage Conditions
-20°C
Notes
For research use only.
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