Prochloraz

Prochloraz is a contact imidazole fungicide that potently inhibits aromatase (IC50 = 40 nM) and acts as an antagonist for estrogen (IC50s = 25 μM) and androgen (IC50 = 4 μM) receptors while activating the aryl hydrocarbon receptor (EC50 = 1 μM) . It is widely used in endocrine disruption research and in vitro toxicology studies to investigate steroidogenesis and receptor-mediated signaling pathways.

Product Specifications

CAS Number

67747-09-5

Product Name Alternative

AhR, androgen, Androgen Receptor, AndrogenReceptor, antifungal, Antifungal, aromatase, estrogen, aryl, Aryl Hydrocarbon Receptor, biosynthesis, BTS 40542, BTS40542, BTS-40542, imidazole, inhibit, Inhibitor, microsomal, Fungal, ergosterol, ERR, Estrogen Receptor, human, EstrogenReceptor, Estrogen Receptor/ERR, hydrocarbon, Sporgon, placenta, Prochloraz, Prelude

Field of Research

Immunology & Inflammation, Infectious Disease & Virology, Metabolism Research

Purity

99.40% (May vary between batches)

Solubility

DMSO:27.5 mg/mL (73.01 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (2.65 mM)

Smiles

C (N (CCOC1=C (Cl) C=C (Cl) C=C1Cl) CCC) (=O) N2C=CN=C2

Molecular Formula

C15H16Cl3N3O2

Molecular Weight

376.67

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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