TH287
TH287 is a selective small molecule inhibitor primarily targeting the nucleotide sanitizing enzyme MTH1 (NUDT1) . It exhibits lower potency against related NUDT family members. This inhibitor is a valuable research tool for studying oxidative DNA damage repair mechanisms in cancer cell lines and in vivo tumor models.
Product Specifications
CAS Number
1609960-30-6
Product Name Alternative
DNASynthesis, DNA/RNA Synthesis, DNA Synthesis, MTH1, RNA Synthesis, RNASynthesis, TH287, TH-287, TH-287 Hydrochloride, TH 287, TH 287 Hydrochloride
Field of Research
Cell Biology, Molecular Biology
Purity
96.95% (May vary between batches)
Solubility
DMSO:49 mg/mL (182.07 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (7.43 mM) ; Ethanol:10 mg/mL (37.16 mM)
Smiles
CNc1cc (nc (N) n1) -c1cccc (Cl) c1Cl
Molecular Formula
C11H10Cl2N4
Molecular Weight
269.13
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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