Atorvastatin
Atorvastatin is an oral HMG-CoA reductase inhibitor that lowers lipids via cytochrome P450 activation. It inhibits human SV-SMC cell proliferation and invasion with IC50 values of 0.39 μM and 2.39 μM, respectively. Research applications include studying cardiovascular disease mechanisms and drug interactions, such as a potential pro-thrombotic effect when combined with clopidogrel.
Product Specifications
CAS Number
134523-00-5
Product Name Alternative
Atorvastatin, Autophagy, Inhibitor, inhibit, HMGCR, HMG-CoA reductase, HMG-CoA Reductase (HMGCR), HMGCoAReductase, HMGCoA Reductase
Field of Research
Cell Biology, Metabolism Research, Pharmacology & Drug Discovery
Purity
98.84% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (5.91 mM) ; DMSO:242.5 mg/mL (434.09 mM)
Smiles
C (NC1=CC=CC=C1) (=O) C=2C (=C (N (CC[C@H] (C[C@H] (CC (O) =O) O) O) C2C (C) C) C3=CC=C (F) C=C3) C4=CC=CC=C4
Molecular Formula
C33H35FN2O5
Molecular Weight
558.64
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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