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Fimepinostat

Fimepinostat (CUDC-907) is an oral dual inhibitor targeting PI3K class I and HDAC enzymes, disrupting the oncogenic PI3K/AKT/mTOR pathway. It has demonstrated antitumor activity in preclinical models of hematologic and solid tumors, supporting its investigation in both in vitro and in vivo cancer research.

Product Specifications

CAS Number

1339928-25-4

Product Name Alternative

PI3K, PI3K/HDAC Inhibitor, Phosphoinositide 3-kinase, inhibit, Inhibitor, Histone deacetylases, HDAC, HDAC3, HDAC11, HDAC1, HDAC10, HDAC2, Fimepinostat, CUDC 907, CUDC907, CUDC-907, Apoptosis

Field of Research

Cell Biology, Epigenetics & Chromatin, Molecular Biology, Signal Transduction

Purity

97.13% (May vary between batches)

Solubility

10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (6.49 mM) ; Ethanol:< 1 mg/mL (insoluble or slightly soluble) ; DMSO:62.5 mg/mL (122.9 mM)

Smiles

COc1ccc (cn1) -c1nc (N2CCOCC2) c2sc (CN (C) c3ncc (cn3) C (=O) NO) cc2n1

Molecular Formula

C23H24N8O4S

Molecular Weight

508.55

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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