Fimepinostat
Fimepinostat (CUDC-907) is an oral dual inhibitor targeting PI3K class I and HDAC enzymes, disrupting the oncogenic PI3K/AKT/mTOR pathway. It has demonstrated antitumor activity in preclinical models of hematologic and solid tumors, supporting its investigation in both in vitro and in vivo cancer research.
Product Specifications
CAS Number
1339928-25-4
Product Name Alternative
PI3K, PI3K/HDAC Inhibitor, Phosphoinositide 3-kinase, inhibit, Inhibitor, Histone deacetylases, HDAC, HDAC3, HDAC11, HDAC1, HDAC10, HDAC2, Fimepinostat, CUDC 907, CUDC907, CUDC-907, Apoptosis
Field of Research
Cell Biology, Epigenetics & Chromatin, Molecular Biology, Signal Transduction
Purity
97.13% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (6.49 mM) ; Ethanol:< 1 mg/mL (insoluble or slightly soluble) ; DMSO:62.5 mg/mL (122.9 mM)
Smiles
COc1ccc (cn1) -c1nc (N2CCOCC2) c2sc (CN (C) c3ncc (cn3) C (=O) NO) cc2n1
Molecular Formula
C23H24N8O4S
Molecular Weight
508.55
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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