W-7 hydrochloride
W-7 hydrochloride is a cell-permeable calmodulin antagonist that inhibits Ca2+/calmodulin-dependent enzymes like myosin light chain kinase and phosphodiesterase. It is widely used in research to study calcium signaling, demonstrating pro-apoptotic and antitumor effects in both cellular and animal models.
Product Specifications
CAS Number
61714-27-0
Product Name Alternative
Myosin, light, inhibit, Inhibitor, chain, Calcium-modulated protein, Apoptosis, apoptosis, antitumor, anti-proliferation, CaMK, CaM, Ca2+, Calmodulin, calmodulin, phosphodiesterase, Phosphodiesterase (PDE), phosphate, W-7 HCl, W7 hydrochloride, W7 Hydrochloride, W-7 Hydrochloride, W-7, W7 HCl, W 7, W 7 HCl, W 7 hydrochloride, W 7 Hydrochloride
Field of Research
Cell Biology, Metabolism Research, Neuroscience, Pharmacology & Drug Discovery, Signal Transduction
Purity
99.63% (May vary between batches)
Solubility
DMSO:250 mg/mL (662.57 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (13.25 mM)
Smiles
C1=CC2=C (C=CC=C2Cl) C (=C1) S (=O) (=O) NCCCCCCN.Cl
Molecular Formula
C16H22Cl2N2O2S
Molecular Weight
377.32
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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