LY2409881 trihydrochloride
LY2409881 trihydrochloride is a potent and selective IKK2 inhibitor with an IC50 of 30 nM, exhibiting over 10-fold selectivity against IKK1 and other common kinases. This compound is a valuable research tool for studying NF-κB signaling in inflammatory and autoimmune disease models, both in cellular assays and in vivo.
Product Specifications
CAS Number
946518-60-1
Product Name Alternative
IKK2, IKK, IkB/IKK, IkB, LY 2409881, LY 2409881 Trihydrochloride, LY-2409881, IκB, Apoptosis
Field of Research
Cell Biology, Signal Transduction
Purity
≥95% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (1.68 mM) ; DMSO:16 mg/mL (26.92 mM) ; Ethanol:< 1 mg/mL (insoluble or slightly soluble) ; H2O:< 1 mg/mL (insoluble or slightly soluble)
Smiles
Cl.Cl.Cl.CN1CCN (CCCNc2ncc (Cl) c (n2) -c2cc3c (cccc3s2) C (=O) NC2CC2) CC1
Molecular Formula
C24H32Cl4N6OS
Molecular Weight
594.43
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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