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LY2409881 trihydrochloride

LY2409881 trihydrochloride is a potent and selective IKK2 inhibitor with an IC50 of 30 nM, exhibiting over 10-fold selectivity against IKK1 and other common kinases. This compound is a valuable research tool for studying NF-κB signaling in inflammatory and autoimmune disease models, both in cellular assays and in vivo.

Product Specifications

CAS Number

946518-60-1

Product Name Alternative

IKK2, IKK, IkB/IKK, IkB, LY 2409881, LY 2409881 Trihydrochloride, LY-2409881, IκB, Apoptosis

Field of Research

Cell Biology, Signal Transduction

Purity

≥95% (May vary between batches)

Solubility

10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (1.68 mM) ; DMSO:16 mg/mL (26.92 mM) ; Ethanol:< 1 mg/mL (insoluble or slightly soluble) ; H2O:< 1 mg/mL (insoluble or slightly soluble)

Smiles

Cl.Cl.Cl.CN1CCN (CCCNc2ncc (Cl) c (n2) -c2cc3c (cccc3s2) C (=O) NC2CC2) CC1

Molecular Formula

C24H32Cl4N6OS

Molecular Weight

594.43

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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