Bedaquiline fumarate
Bedaquiline fumarate (TMC207) is a diarylquinoline-class antibiotic that inhibits mycobacterial ATP synthase, blocking its proton pump. It is a first-in-class therapeutic for Mycobacterium tuberculosis, validated in both in vitro assays and in vivo models of tuberculosis infection.
Product Specifications
CAS Number
845533-86-0
Product Name Alternative
TMC 207, TMC207, TMC-207, R 207910, R 403323, R403323, R-403323, R207910, R-207910, inhibit, Inhibitor, Bacterial, Antibiotic, Bedaquiline fumarate, Bedaquiline Fumarate, Bedaquiline
Field of Research
Infectious Disease & Virology, Pharmacology & Drug Discovery
Purity
98.88% (May vary between batches)
Solubility
DMSO:27.5 mg/mL (40.95 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (2.98 mM)
Smiles
OC (=O) \C=C\C (O) =O.COc1nc2ccc (Br) cc2cc1[C@@H] (c1ccccc1) [C@@] (O) (CCN (C) C) c1cccc2ccccc12
Molecular Formula
C36H35BrN2O6
Molecular Weight
671.59
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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