Ispinesib
Ispinesib (SB-715992) is a quinazolinone-derived, potent, and reversible inhibitor of kinesin spindle protein (KSP) with antineoplastic activity. It is widely used in cancer research to study mitotic arrest and has demonstrated efficacy in both in vitro cell-based assays and in vivo xenograft tumor models.
Product Specifications
CAS Number
336113-53-2
Product Name Alternative
CK0238273, CK-0238273, CK 0238273, Apoptosis, Inhibitor, KSP (HsEg5), Kinesin, Ispinesib, inhibit, SB 715992, SB715992, SB-715992
Field of Research
Cell Biology, Signal Transduction
Purity
98.00% (May vary between batches)
Solubility
DMSO:95 mg/mL (183.73 mM) ; Ethanol:95 mg/mL (183.73 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (6.38 mM)
Smiles
CC (C) [C@@H] (N (CCCN) C (=O) c1ccc (C) cc1) c1nc2cc (Cl) ccc2c (=O) n1Cc1ccccc1
Molecular Formula
C30H33ClN4O2
Molecular Weight
517.06
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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