JQ1 (+)
(+) -JQ-1 is a potent, selective, and reversible BET bromodomain inhibitor, notably targeting BRD4. It has been widely used in vitro and in vivo to study roles in oncology, immunology, and inflammation, where it demonstrates effects such as inducing autophagy and inhibiting cellular proliferation.
Product Specifications
CAS Number
1268524-70-4
Product Name Alternative
Autophagy, (+) JQ1, (+) JQ 1, BRD4 (2), BRD4 (1), JQ 1, JQ1, JQ-1, Ligands for Target Protein for PROTAC, LigandsforTargetProteinforPROTAC, Inhibitor, inhibit, Epigenetic Reader Domain, EpigeneticReaderDomain, Target Protein-binding Moiety
Field of Research
Epigenetics & Chromatin
Purity
>98%
Bioactivity
Bromodomain inhibitor
Form
Powder
Solubility
Soluble in DMSO (up to 60 mg/ml) or in Ethanol (up to 46 mg/ml)
Smiles
CC=1C2=C (N3C ([C@H] (CC (OC (C) (C) C) =O) N=C2C4=CC=C (Cl) C=C4) =NN=C3C) SC1C
Molecular Formula
C23H25ClN4O2S
Molecular Weight
457.0
Storage Conditions
RT
Notes
For research use only.
Other Product Names
(6S) -4- (4-Chlorophenyl) -2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine-6-acetic acid 1,1-dimethylethyl ester
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