AEE788
AEE788 (NVP-AEE 788) is a small molecule inhibitor investigated in preclinical cancer research, particularly for glioblastoma and CNS tumors. It functions by targeting EGFR and VEGFR tyrosine kinases, and its antitumor efficacy has been studied in both in vitro cell assays and in vivo animal models.
Product Specifications
CAS Number
497839-62-0
Product Name Alternative
C-Fms, cFms, c-Abl, BcrAbl, Apoptosis, AEE 788, AEE788, AEE-788, Inhibitor, HER2/ErbB2, HER1, Epidermal growth factor receptor, EGFR, ErbB-1, FLT1, NVP-AEE 788, NVP-AEE788, NVP-AEE-788, inhibit
Field of Research
Cardiovascular Research, Cell Biology, Signal Transduction
Purity
98.00% (May vary between batches)
Solubility
DMSO:82 mg/mL (186.12 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (7.49 mM) ; Ethanol:< 1 mg/mL (insoluble or slightly soluble)
Smiles
CCN1CCN (Cc2ccc (cc2) -c2cc3c (N[C@H] (C) c4ccccc4) ncnc3[nH]2) CC1
Molecular Formula
C27H32N6
Molecular Weight
440.58
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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