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ML281

ML281 is a highly selective small molecule inhibitor of STK33, demonstrating potent activity with an IC50 of 14 nM. It is a valuable research tool for studying STK33 function in cancer biology and has been utilized in both in vitro cellular assays and in vivo xenograft models to investigate oncogenic signaling pathways.

Product Specifications

CAS Number

1404437-62-2

Product Name Alternative

Inhibitor, ML 281, ML281, ML-281, inhibit, SerineProtease, Serine Protease, STK33

Field of Research

Protein Biochemistry

Purity

99.12% (May vary between batches)

Solubility

H2O:< 1 mg/mL (insoluble or slightly soluble) ; DMSO:50 mg/mL (128.38 mM)

Smiles

CC (C) c1ccc (NC (=O) c2cccs2) c (c1) -c1nc2ccccc2[nH]c1=O

Molecular Formula

C22H19N3O2S

Molecular Weight

389.47

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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