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Vicriviroc maleate

Vicriviroc maleate is a potent piperazine-based CCR5 antagonist developed for HIV-1 treatment, demonstrating an IC50 of 0.91 nM. It has been investigated in clinical trials and is a valuable research tool for studying CCR5-mediated viral entry in both cellular and animal models of HIV infection.

Product Specifications

CAS Number

599179-03-0

Product Name Alternative

Inhibit, HIV, HIV Protease, HIVProtease, Inhibitor, Human immunodeficiency virus, CCR, CC chemokine receptor, CCR5, SCH417690, SCH-417690, SCH-417690 (maleate), SCH-D, SCH-D (maleate), SCH 417690, Vicriviroc, Vicriviroc Maleate, Vicriviroc maleate

Field of Research

Immunology & Inflammation, Infectious Disease & Virology, Pharmacology & Drug Discovery, Protein Biochemistry

Purity

97.27% (May vary between batches)

Solubility

H2O:25 mg/mL (38.48 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (3.08 mM) ; DMSO:50 mg/mL (76.96 mM)

Smiles

OC (=O) \C=C/C (O) =O.COC[C@H] (N1CCN (C[C@@H]1C) C1 (C) CCN (CC1) C (=O) c1c (C) ncnc1C) c1ccc (cc1) C (F) (F) F

Molecular Formula

C32H42F3N5O6

Molecular Weight

649.7

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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