S107
S107 is a 1,4-benzothiazepine derivative that selectively targets and stabilizes RyR2 channels. It functions by increasing the binding affinity of calstabin2 to PKA-phosphorylated or mutant channels. This action makes it a valuable research tool for studying cardiac arrhythmias and heart failure in both cellular and animal models.
Product Specifications
CAS Number
927871-76-9
Product Name Alternative
S 107, S107, S-107
Field of Research
Metabolism Research, Pharmacology & Drug Discovery
Purity
99.63% (May vary between batches)
Solubility
DMSO:130 mg/mL (621.09 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (9.56 mM)
Smiles
COc1ccc2SCCN (C) Cc2c1
Molecular Formula
C11H15NOS
Molecular Weight
209.31
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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