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Merimepodib

Merimepodib (VX-497) is a potent, non-competitive inhibitor of the enzyme IMPDH, a key target in nucleotide biosynthesis. It has been utilized in research exploring antiviral and immunosuppressive mechanisms, with studies conducted both in vitro and in animal models of autoimmune and inflammatory diseases.

Product Specifications

CAS Number

198821-22-6

Product Name Alternative

Merimepodib, HBV, HCV, HCV Protease, HCVProtease, Hepatitis B virus, Hepatitis C virus, inhibit, Inhibitor, IMPDH, MMPD, Antiviral, VI21497, VI-21497, VI 21497, VX 497, VX497, VX-497

Field of Research

Immunology & Inflammation, Infectious Disease & Virology, Metabolism Research, Protein Biochemistry

Purity

98.77% (May vary between batches)

Solubility

10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.42 mM) ; DMSO:235 mg/mL (519.38 mM)

Smiles

COc1cc (NC (=O) Nc2cccc (CNC (=O) O[C@H]3CCOC3) c2) ccc1-c1cnco1

Molecular Formula

C23H24N4O6

Molecular Weight

452.46

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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