Merimepodib
Merimepodib (VX-497) is a potent, non-competitive inhibitor of the enzyme IMPDH, a key target in nucleotide biosynthesis. It has been utilized in research exploring antiviral and immunosuppressive mechanisms, with studies conducted both in vitro and in animal models of autoimmune and inflammatory diseases.
Product Specifications
CAS Number
198821-22-6
Product Name Alternative
Merimepodib, HBV, HCV, HCV Protease, HCVProtease, Hepatitis B virus, Hepatitis C virus, inhibit, Inhibitor, IMPDH, MMPD, Antiviral, VI21497, VI-21497, VI 21497, VX 497, VX497, VX-497
Field of Research
Immunology & Inflammation, Infectious Disease & Virology, Metabolism Research, Protein Biochemistry
Purity
98.77% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.42 mM) ; DMSO:235 mg/mL (519.38 mM)
Smiles
COc1cc (NC (=O) Nc2cccc (CNC (=O) O[C@H]3CCOC3) c2) ccc1-c1cnco1
Molecular Formula
C23H24N4O6
Molecular Weight
452.46
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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