Thiomyristoyl
Thiomyristoyl is a potent and highly selective SIRT2 inhibitor with an IC50 of 28 nM, showing over 3,500-fold selectivity against SIRT1 and no activity against SIRT3. This inhibitor is a valuable chemical probe for studying SIRT2's role in cancer, neurodegenerative diseases, and aging in both cellular and animal models.
Product Specifications
CAS Number
1429749-41-6
Product Name Alternative
Thiomyristoyl, SIRT1, SIRT2, Sirtuin, inhibit, Inhibitor
Field of Research
Epigenetics & Chromatin, Molecular Biology
Purity
99.13% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (6.87 mM) ; Chloroform:Soluble; DMSO:100 mg/mL (171.87 mM) ; H2O:< 1 mg/mL (insoluble or slightly soluble)
Smiles
CCCCCCCCCCCCCC (=S) NCCCC[C@H] (NC (=O) OCc1ccccc1) C (=O) Nc1ccccc1
Molecular Formula
C34H51N3O3S
Molecular Weight
581.85
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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