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Thiomyristoyl

Thiomyristoyl is a potent and highly selective SIRT2 inhibitor with an IC50 of 28 nM, showing over 3,500-fold selectivity against SIRT1 and no activity against SIRT3. This inhibitor is a valuable chemical probe for studying SIRT2's role in cancer, neurodegenerative diseases, and aging in both cellular and animal models.

Product Specifications

CAS Number

1429749-41-6

Product Name Alternative

Thiomyristoyl, SIRT1, SIRT2, Sirtuin, inhibit, Inhibitor

Field of Research

Epigenetics & Chromatin, Molecular Biology

Purity

99.13% (May vary between batches)

Solubility

10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (6.87 mM) ; Chloroform:Soluble; DMSO:100 mg/mL (171.87 mM) ; H2O:< 1 mg/mL (insoluble or slightly soluble)

Smiles

CCCCCCCCCCCCCC (=S) NCCCC[C@H] (NC (=O) OCc1ccccc1) C (=O) Nc1ccccc1

Molecular Formula

C34H51N3O3S

Molecular Weight

581.85

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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