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JNJ-42153605

JNJ-42153605 is a potent and selective positive allosteric modulator of the metabotropic glutamate receptor 2 (mGlu2), exhibiting an EC50 of 17 nM. This research compound is utilized in vitro and in vivo to investigate the role of mGlu2 in neuropsychiatric disorders such as anxiety and schizophrenia.

Product Specifications

CAS Number

1254977-87-1

Product Name Alternative

Metabotropic glutamate receptors, mGluR2 PAM, mGluR, Inhibitor, JNJ42153605, JNJ-42153605, JNJ 42153605, inhibit

Field of Research

Neuroscience

Purity

97.25% (May vary between batches)

Solubility

DMSO:Slightly soluble

Smiles

FC (F) (F) c1c (ccn2c (CC3CC3) nnc12) N1CCC (CC1) c1ccccc1

Molecular Formula

C22H23F3N4

Molecular Weight

400.44

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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