JNJ-42153605
JNJ-42153605 is a potent and selective positive allosteric modulator of the metabotropic glutamate receptor 2 (mGlu2), exhibiting an EC50 of 17 nM. This research compound is utilized in vitro and in vivo to investigate the role of mGlu2 in neuropsychiatric disorders such as anxiety and schizophrenia.
Product Specifications
CAS Number
1254977-87-1
Product Name Alternative
Metabotropic glutamate receptors, mGluR2 PAM, mGluR, Inhibitor, JNJ42153605, JNJ-42153605, JNJ 42153605, inhibit
Field of Research
Neuroscience
Purity
97.25% (May vary between batches)
Solubility
DMSO:Slightly soluble
Smiles
FC (F) (F) c1c (ccn2c (CC3CC3) nnc12) N1CCC (CC1) c1ccccc1
Molecular Formula
C22H23F3N4
Molecular Weight
400.44
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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