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VER-49009

VER-49009 (CCT 129397) is a highly potent small molecule inhibitor of Hsp90, exhibiting an IC50 of 25 nM and a Kd of 78 nM. It is a valuable research tool for studying oncogenic client protein degradation and has demonstrated antitumor activity in both cellular assays and in vivo xenograft models.

Product Specifications

CAS Number

558640-51-0

Product Name Alternative

CCT 129397, CCT129397, CCT-129397, Heat shock proteins, Hsp90, HSP, Inhibitor, inhibit, VER49009, VER-49009, VER 49009

Field of Research

Metabolism Research, Signal Transduction

Purity

99.36% (May vary between batches)

Solubility

DMSO:100 mg/mL (257.85 mM) ; H2O:< 1 mg/mL (insoluble or slightly soluble) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (10.31 mM) ; Ethanol:< 1 mg/mL (insoluble or slightly soluble)

Smiles

CCNC (=O) c1n[nH]c (c1-c1ccc (OC) cc1) -c1cc (Cl) c (O) cc1O

Molecular Formula

C19H18ClN3O4

Molecular Weight

387.82

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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