Vesnarinone
Vesnarinone (Arkin, INN) is a mixed phosphodiesterase 3 inhibitor and ion-channel modifier exhibiting dose-dependent positive inotropic effects with minimal heart rate reduction. Its research applications extend to studying p53-mediated cell cycle arrest, as it induces p21 expression to suppress proliferation and promote apoptosis in vitro.
Product Specifications
CAS Number
81840-15-5
Product Name Alternative
Heart failure, HIV Protease, HIV, HIVProtease, Inhibitor, inhibit, PDE, OPC8212, OPC-8212, OPC 8212, oral activity, OSC3, OSC4, OSC5, Arkin, phosphodiesterase 3, Phosphodiesterase (PDE), phosphodiesterase, positive inotropic activity, Piteranometozine, Vesnarinone
Field of Research
Infectious Disease & Virology, Metabolism Research, Pharmacology & Drug Discovery, Protein Biochemistry
Purity
96.69% (May vary between batches)
Solubility
DMSO:3.96 mg/mL (10.01 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (2.53 mM)
Smiles
COc1ccc (cc1OC) C (=O) N1CCN (CC1) c1ccc2NC (=O) CCc2c1
Molecular Formula
C22H25N3O4
Molecular Weight
395.45
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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