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EFT508

Tomivosertib (eFT508) is a highly selective, potent dual inhibitor of MNK1 and MNK2 kinases, exhibiting IC50 values in the low nanomolar range. It is widely used in preclinical research to investigate MNK's role in oncogenesis and immune modulation, demonstrating antitumor activity in both cellular assays and in vivo animal models.

Product Specifications

CAS Number

1849590-01-7

Product Name Alternative

Tomivosertib

Field of Research

Neuroscience

Purity

>98%

Form

Powder

Solubility

Soluble in DMSO (2 mg/ml with warming)

Smiles

Cc1cc (Nc2cc (N) ncn2) c (=O) n2c1C (=O) NC21CCCCC1

Molecular Formula

C17H20N6O2

Molecular Weight

340.4

Storage Conditions

-20°C

Notes

For research use only.

Other Product Names

6-[ (6-Aminopyrimidin-4-yl) amino]-8-methylspiro[2H-imidazo[1,5-a]pyridine-3,1’-cyclohexane]-1,5-dione

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