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CFMTI

CFMTI is a highly potent and selective allosteric antagonist of metabotropic glutamate receptor 1 (mGluR1), exhibiting an IC50 of 2.6 nM with over 2000-fold selectivity versus mGluR5. This tool compound is valuable for investigating mGluR1 function in neurological research, including studies on pain, neurodegeneration, and synaptic plasticity in both cellular and animal models.

Product Specifications

CAS Number

864864-17-5

Product Name Alternative

Inhibitor, inhibit, Metabotropic glutamate receptors, mGluR, CFMTI

Field of Research

Neuroscience

Purity

97.23% (May vary between batches)

Solubility

DMSO:4.62 mg/mL (13.22 mM)

Smiles

Cc1c (nnn1-c1cccnc1F) -c1ccc2C (=O) N (Cc2c1) C1CC1

Molecular Formula

C19H16FN5O

Molecular Weight

349.36

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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