CFMTI
CFMTI is a highly potent and selective allosteric antagonist of metabotropic glutamate receptor 1 (mGluR1), exhibiting an IC50 of 2.6 nM with over 2000-fold selectivity versus mGluR5. This tool compound is valuable for investigating mGluR1 function in neurological research, including studies on pain, neurodegeneration, and synaptic plasticity in both cellular and animal models.
Product Specifications
CAS Number
864864-17-5
Product Name Alternative
Inhibitor, inhibit, Metabotropic glutamate receptors, mGluR, CFMTI
Field of Research
Neuroscience
Purity
97.23% (May vary between batches)
Solubility
DMSO:4.62 mg/mL (13.22 mM)
Smiles
Cc1c (nnn1-c1cccnc1F) -c1ccc2C (=O) N (Cc2c1) C1CC1
Molecular Formula
C19H16FN5O
Molecular Weight
349.36
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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