Dasabuvir
Dasabuvir (ABT-333) is a non-nucleoside inhibitor targeting the HCV NS5B RNA-dependent RNA polymerase, thereby blocking viral replication. It is used in research applications, including in vitro antiviral assays and in vivo studies within combination therapies for hepatitis C, to investigate mechanisms of action and resistance.
Product Specifications
CAS Number
1132935-63-7
Product Name Alternative
Inhibitor, NS5B polymerase, inhibit, genotype, Hepatitis C virus, HCV genotype 1 infections, HCV, HCV Protease, HCV polymerase, HCVProtease, ABT 333, ABT333, ABT-333, DNA/RNA Synthesis, Dasabuvir, RNA
Field of Research
Cell Biology, Infectious Disease & Virology, Molecular Biology, Pharmacology & Drug Discovery, Protein Biochemistry
Purity
99.52% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.05 mM) ; DMSO:60 mg/mL (121.56 mM)
Smiles
COc1c (cc (cc1C (C) (C) C) -n1ccc (=O) [nH]c1=O) -c1ccc2cc (NS (C) (=O) =O) ccc2c1
Molecular Formula
C26H27N3O5S
Molecular Weight
493.57
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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