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Tasimelteon

Tasimelteon (BMS-214778) is a selective melatonin receptor agonist used to treat Non-24-Hour Sleep-Wake Disorder. It is widely applied in circadian rhythm research, with studies demonstrating its in vivo efficacy in entraining sleep-wake cycles in blind individuals and its in vitro binding affinity for MT1 and MT2 receptors.

Product Specifications

CAS Number

609799-22-6

Product Name Alternative

Melatonin Receptor, MelatoninReceptor, Inhibitor, orally, MT1, MT1 receptor, MT Receptor, MT2, MT2 receptor, MTReceptor, inhibit, Non-24, DMRA, circadian, BMS 214778, BMS214778, BMS-214778, Tasimelteon, regulator, VEC162, VEC-162, VEC 162

Field of Research

Neuroscience, Pharmacology & Drug Discovery

Purity

98.08% (May vary between batches)

Solubility

DMSO:50 mg/mL (203.82 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (8.15 mM)

Smiles

CCC (=O) NC[C@@H]1C[C@H]1c1cccc2OCCc12

Molecular Formula

C15H19NO2

Molecular Weight

245.32

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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