MC-Val-Cit-PABC-PNP
MC-Val-Cit-PABC-PNP is a protease-cleavable linker used in antibody-drug conjugates (ADCs) like brentuximab vedotin. It enables targeted drug release in cancer research, facilitating the study of payload delivery in both in vitro and in vivo experimental models.
Product Specifications
CAS Number
159857-81-5
Product Name Alternative
Inhibitor, inhibit, Maleimidocaproyl-L-valine-L-citrulline-p-aminobenzyl alcohol p-nitrophenyl carbonate, MC Val Cit PABC PNP, MCValCitPABCPNP, MC-Val-Cit-PABC-PNP, ADC Linkers, ADCLinker, ADC Linker, Antibody-drug conjugates linkers
Field of Research
Neuroscience, Signal Transduction
Purity
97.20% (May vary between batches)
Solubility
DMSO:37 mg/mL (50.15 mM)
Smiles
[C@H] (C (NC1=CC=C (COC (OC2=CC=C (N (=O) =O) C=C2) =O) C=C1) =O) (NC ([C@@H] (NC (CCCCCN3C (=O) C=CC3=O) =O) C (C) C) =O) CCCNC (N) =O
Molecular Formula
C35H43N7O11
Molecular Weight
737.76
Storage Conditions
-20°C
Notes
For research use only.
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