AZD5153 6-Hydroxy-2-naphthoic acid
AZD5153 is a potent, triazolopyridazine-based dual BRD4 and BET bromodomain inhibitor. It is utilized in cancer research to probe BET protein function and has demonstrated antitumor activity in both cellular assays and in vivo models.
Product Specifications
CAS Number
1869912-40-2
Product Name Alternative
BD1-BRD4, AZD 5153, AZD-5153 6-Hydroxy-2-naphthoic acid, AZD5153 6-Hydroxy-2-naphthoic acid, AZD-5153 HNT, AZD-5153 HNT salt, AZD5153, AZD-5153, AZD5153 6 Hydroxy 2 naphthoic acid, AZD5153 6Hydroxy2naphthoic acid, FL-BRD4, Epigenetic Reader Domain, EpigeneticReaderDomain
Field of Research
Epigenetics & Chromatin
Purity
≥95% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (4.94 mM) ; DMSO:250 mg/mL (374.39 mM) ; Ethanol:26 mg/mL (38.94 mM) ; H2O:< 1 mg/mL (insoluble or slightly soluble)
Smiles
OC (=O) c1ccc2cc (O) ccc2c1.COc1nnc2ccc (nn12) N1CCC (CC1) c1ccc (OCCN2CCN (C) C (=O) [C@H]2C) cc1
Molecular Formula
C25H33N7O3·C11H8O3
Molecular Weight
667.75
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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