EDO-S101
EDO-S101 (Tinostamustine) is a potent pan-HDAC inhibitor, exhibiting IC50 values of 9, 9, and 25 nM against HDAC1, HDAC2, and HDAC3, respectively. It is utilized in cancer research for its dual alkylating and HDAC inhibitory activity, showing efficacy in both in vitro and in vivo preclinical studies against hematological and solid tumor models.
Product Specifications
CAS Number
1236199-60-2
Product Name Alternative
Minomustine, inhibit, Inhibitor, EDO-S 101, EDOS101, EDO-S101, EDO-S-101, EDO S101, HDAC8, HDAC6, HDAC, HDAC1, HDAC3, HDAC2, Histone deacetylases, Tinostamustine
Field of Research
Epigenetics & Chromatin, Molecular Biology
Purity
98.02% (May vary between batches)
Solubility
DMSO:30 mg/mL (72.23 mM)
Smiles
CN1C=2C (=CC (N (CCCl) CCCl) =CC2) N=C1CCCCCCC (NO) =O
Molecular Formula
C19H28Cl2N4O2
Molecular Weight
415.36
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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