GSK269962A
GSK269962A hydrochloride is a potent and selective ROCK inhibitor, exhibiting IC50 values of 1.6 nM for ROCK1 and 4 nM for ROCK2. It is widely used in cardiovascular and neurological research to investigate Rho kinase signaling pathways in both cellular and animal models.
Product Specifications
CAS Number
850664-21-0
Product Name Alternative
GSK269962B, GSK269962, GSK-269962, GSK269962A, GSK-269962A, GSK269962A HCl, GSK 269962, MSK1, pressure, RSK1, S6 Kinase, S6Kinase, ROCK, ROCK1, ROCK2, vasodilatory
Field of Research
Cell Biology, Signal Transduction, Stem Cell & Developmental Biology
Purity
98.63% (May vary between batches)
Solubility
DMSO:57.1 mg/mL (100.07 mM) ; Ethanol:6 mg/mL (10.52 mM) ; H2O:< 1 mg/mL (insoluble or slightly soluble) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (3.51 mM)
Smiles
CCn1c (nc2cnc (Oc3cccc (NC (=O) c4ccc (OCCN5CCOCC5) cc4) c3) cc12) -c1nonc1N
Molecular Formula
C29H30N8O5
Molecular Weight
570.6
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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