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GSK269962A

GSK269962A hydrochloride is a potent and selective ROCK inhibitor, exhibiting IC50 values of 1.6 nM for ROCK1 and 4 nM for ROCK2. It is widely used in cardiovascular and neurological research to investigate Rho kinase signaling pathways in both cellular and animal models.

Product Specifications

CAS Number

850664-21-0

Product Name Alternative

GSK269962B, GSK269962, GSK-269962, GSK269962A, GSK-269962A, GSK269962A HCl, GSK 269962, MSK1, pressure, RSK1, S6 Kinase, S6Kinase, ROCK, ROCK1, ROCK2, vasodilatory

Field of Research

Cell Biology, Signal Transduction, Stem Cell & Developmental Biology

Purity

98.63% (May vary between batches)

Solubility

DMSO:57.1 mg/mL (100.07 mM) ; Ethanol:6 mg/mL (10.52 mM) ; H2O:< 1 mg/mL (insoluble or slightly soluble) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (3.51 mM)

Smiles

CCn1c (nc2cnc (Oc3cccc (NC (=O) c4ccc (OCCN5CCOCC5) cc4) c3) cc12) -c1nonc1N

Molecular Formula

C29H30N8O5

Molecular Weight

570.6

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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