Halofuginone HBr
Halofuginone hydrobromide is a semisynthetic alkaloid that suppresses collagen type I and MMP-2 gene expression. This inhibition of key fibrotic and angiogenic promoters makes it a valuable research tool for studying fibroproliferative diseases, tumor stroma, and cancer progression in both cellular and animal models.
Product Specifications
CAS Number
64924-67-0
Product Name Alternative
NSC 713205
Field of Research
Cardiovascular Research, Cell Biology, Immunology & Inflammation
Purity
> 95%
Bioactivity
Prolyl-tRNA synthase inhibitor
Form
Powder
Solubility
Soluble in DMSO (up to 50 mg/ml)
Smiles
Br.O[C@H]1CCCN[C@@H]1CC (=O) Cn1cnc2cc (Br) c (Cl) cc2c1=O
Molecular Formula
C16H17BrClN3O3 • HBr
Molecular Weight
495.6
Storage Conditions
-20°C
Notes
For research use only.
Other Product Names
(2R*,3S*) -7-Bromo-6-chloro-3-[3- (3-hydroxy-2-piperidinyl) -2-oxopropyl]-4-3H-quinazolinone hydrobromide
Available Sizes
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