TRC051384
TRC051384 is a small molecule HSP70 inducer that activates HSF1, elevating chaperone and anti-inflammatory activity. It has demonstrated neuroprotective effects in a rat transient ischemic stroke model, increasing neuronal Hsp72 expression and survival. This compound is a valuable research tool for studying heat shock response mechanisms in both in vivo and in vitro models of neuroinflammation and ischemia.
Product Specifications
CAS Number
867164-40-7
Product Name Alternative
Inhibit, HSP70, Inhibitor, Heat shock proteins, HSP, TRC051384, TRC-051384, TRC 051384
Field of Research
Metabolism Research, Signal Transduction
Purity
92.66% (May vary between batches)
Solubility
DMSO:16.67 mg/mL (35.81 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.3 mM)
Smiles
O=C (NCCN1CCOCC1) Nc1ccc (cc1) C (=O) \C=C\c1cccc (n1) N1CCOCC1
Molecular Formula
C25H31N5O4
Molecular Weight
465.54
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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