AZD1283
AZD1283 is a potent and selective P2Y12 receptor antagonist with an IC50 of 11 nM, demonstrating effective antithrombotic activity and inhibition of ADP-induced platelet aggregation in vivo. It shows a favorable therapeutic index (≥10) by achieving efficacy at doses lower than those significantly increasing bleeding time, making it a useful research tool for cardiovascular and thrombosis studies.
Product Specifications
CAS Number
919351-41-0
Product Name Alternative
Antiplatelet aggregation, antithrombotic, AZD 1283, AZD1283, AZD-1283, inhibit, P2YReceptor, P2Y12, P2Y Receptor, P2Y, Inhibitor, thromboembolic
Field of Research
Neuroscience, Pharmacology & Drug Discovery
Purity
98.29% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.25 mM) ; DMSO:22.5 mg/mL (47.82 mM)
Smiles
CCOC (=O) c1cc (C#N) c (nc1C) N1CCC (CC1) C (=O) NS (=O) (=O) Cc1ccccc1
Molecular Formula
C23H26N4O5S
Molecular Weight
470.54
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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