GSK583
GSK583 is a potent and selective inhibitor of RIP2 kinase, exhibiting an IC50 of 5 nM. This compound is a valuable research tool for studying the NOD signaling pathway in both cellular and animal models of inflammatory and autoimmune diseases.
Product Specifications
CAS Number
1346547-00-9
Product Name Alternative
Inhibitor, GSK 583, GSK583, GSK-583, inhibit, RIP3, RIP kinase, RIP1, RIPkinase, RIPK, Receptor-interacting protein kinases
Field of Research
Immunology & Inflammation
Purity
>98%
Bioactivity
RIP2 kinase inhibitor
Form
Powder
Solubility
Soluble in DMSO (up to 25 mg/ml)
Smiles
CC (C) (C) S (=O) (=O) c1ccc2nccc (Nc3n[nH]c4ccc (F) cc34) c2c1
Molecular Formula
C20H19FN4O2S
Molecular Weight
398.4
Storage Conditions
-20°C
Notes
For research use only.
Other Product Names
6-tert-Butylsulfonyl-N- (5-fluoro-1H-indazol-3-yl) quinoline-4-amine
Available Sizes
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