Lu AF21934
Lu AF21934 is a selective positive allosteric modulator of the mGlu4 receptor with an IC50 of 500 nM (human) and demonstrated brain penetration. This compound is a valuable research tool for investigating the role of mGlu4 in neurological disorders, supporting both in vitro and in vivo experimental studies.
Product Specifications
CAS Number
1445605-23-1
Product Name Alternative
Inhibitor, inhibit, Metabotropic glutamate receptors, mGluR4, mGluR, Lu AF21934, Lu AF-21934, Lu AF 21934
Field of Research
Neuroscience
Purity
97.96% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (6.35 mM) ; DMSO:16.67 mg/mL (52.89 mM)
Smiles
NC (=O) [C@@H]1CCCC[C@@H]1C (=O) Nc1ccc (Cl) c (Cl) c1
Molecular Formula
C14H16Cl2N2O2
Molecular Weight
315.2
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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