SHP099 hydrochloride
SHP099 hydrochloride is a potent and selective oral SHP2 inhibitor with an IC50 of 70 nM. It effectively blocks downstream ERK1/2 signaling in cancer cells and is widely used in vitro and in vivo to study oncogenic pathways in cancers driven by RTK or RAS signaling.
Product Specifications
CAS Number
2200214-93-1
Product Name Alternative
Inhibit, Inhibitor, SHP 099, SHP 099 Hydrochloride, SHP099 Hydrochloride, SHP099 hydrochloride, SHP-099 Hydrochloride, SHP-099 hydrochloride, SHP099, SHP-099, SHP-2, Phosphatase
Field of Research
Metabolism Research
Purity
99.13% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween-80+45% Saline:2.5 mg/mL (6.43 mM) ; Methanol:15 mg/mL (38.59 mM) ; DMSO:32 mg/mL (82.32 mM) ; H2O:10 mg/mL (25.73 mM)
Smiles
Cl.CC1 (N) CCN (CC1) c1cnc (c (N) n1) -c1cccc (Cl) c1Cl
Molecular Formula
C16H20Cl3N5
Molecular Weight
388.72
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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