Epacadostat
Epacadostat (INCB 024360) is a potent and selective small molecule inhibitor of indoleamine 2,3-dioxygenase 1 (IDO1), exhibiting an IC50 of 71.8 nM. It is widely used in cancer immunology research to investigate the tumor microenvironment and has been evaluated in both in vitro assays and in vivo preclinical models.
Product Specifications
CAS Number
1204669-58-8
Product Name Alternative
INCB024360
Field of Research
Immunology & Inflammation
Purity
>98%
Bioactivity
IDO1 inhibitor
Form
Powder
Solubility
Soluble in DMSO (up to at least 25 mg/ml)
Smiles
NS (=O) (=O) NCCNc1nonc1\C (Nc1ccc (F) c (Br) c1) =N\O
Molecular Formula
C11H13BrFN7O4S
Molecular Weight
438.2
Storage Conditions
-20°C
Notes
For research use only.
Other Product Names
N- (3-Bromo-4-fluorophenyl) -N’-hydroxy-4-{[2- (sulfamoylamino) ethyl]amino}-1,2,5-oxadiazole-3-carboximidamide
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