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Avadomide

Avadomide (CC-122) is an orally bioavailable cereblon-modulating agent with potential antineoplastic properties. It is utilized in cancer research, particularly in hematological malignancies, to study its immunomodulatory and tumoricidal effects in both in vitro and in vivo experimental models.

Product Specifications

CAS Number

1015474-32-4

Product Name Alternative

Diffuse, DLBCL, E2Enzyme, E3 Enzyme, E3 Ligase, E2 conjugating enzyme, E2 Enzyme, E1Enzyme, E1 Enzyme, E1/E2/E3 Enzyme, E1 activating enzyme, CC 122, CC-122, CC122, cereblon, Apoptosis, Avadomide, antitumor, B-cell, Inhibitor, large, E3 ligating enzyme, E3Enzyme, LigandforE3Ligase, ligase, Ligand for E3 Ligase, inhibit, immunomodulatory, lymphoma, orally, Ubiquitin conjugating enzyme, Ubiquitin ligase, Ubiquitin activating enzyme

Field of Research

Cell Biology, Pharmacology & Drug Discovery, Protein Biochemistry, Signal Transduction

Purity

99.07% (May vary between batches)

Solubility

10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (6.99 mM) ; Ethanol:1 mg/mL (3.49 mM) ; DMSO:52 mg/mL (181.63 mM)

Smiles

Cc1nc2cccc (N) c2c (=O) n1C1CCC (=O) NC1=O

Molecular Formula

C14H14N4O3

Molecular Weight

286.29

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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