Avadomide
Avadomide (CC-122) is an orally bioavailable cereblon-modulating agent with potential antineoplastic properties. It is utilized in cancer research, particularly in hematological malignancies, to study its immunomodulatory and tumoricidal effects in both in vitro and in vivo experimental models.
Product Specifications
CAS Number
1015474-32-4
Product Name Alternative
Diffuse, DLBCL, E2Enzyme, E3 Enzyme, E3 Ligase, E2 conjugating enzyme, E2 Enzyme, E1Enzyme, E1 Enzyme, E1/E2/E3 Enzyme, E1 activating enzyme, CC 122, CC-122, CC122, cereblon, Apoptosis, Avadomide, antitumor, B-cell, Inhibitor, large, E3 ligating enzyme, E3Enzyme, LigandforE3Ligase, ligase, Ligand for E3 Ligase, inhibit, immunomodulatory, lymphoma, orally, Ubiquitin conjugating enzyme, Ubiquitin ligase, Ubiquitin activating enzyme
Field of Research
Cell Biology, Pharmacology & Drug Discovery, Protein Biochemistry, Signal Transduction
Purity
99.07% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (6.99 mM) ; Ethanol:1 mg/mL (3.49 mM) ; DMSO:52 mg/mL (181.63 mM)
Smiles
Cc1nc2cccc (N) c2c (=O) n1C1CCC (=O) NC1=O
Molecular Formula
C14H14N4O3
Molecular Weight
286.29
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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