SHP099
SHP099 is a potent, selective, and orally bioavailable SHP2 inhibitor with cellular activity, demonstrating dose-dependent inhibition of downstream signaling and antitumor efficacy in xenograft models. It is widely used in cancer research to investigate SHP2's role in RAS/MAPK pathway-driven tumors through both in vitro and in vivo studies.
Product Specifications
CAS Number
1801747-42-1
Product Name Alternative
Inhibitor, inhibit, Phosphatase, SHP-2, SHP-099, SHP099 free base, SHP099, SHP 099, PERK
Field of Research
Cell Biology, Metabolism Research, Signal Transduction
Purity
98.73% (May vary between batches)
Solubility
DMSO:15.8 mg/mL (44.85 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (2.84 mM)
Smiles
CC1 (N) CCN (CC1) c1cnc (c (N) n1) -c1cccc (Cl) c1Cl
Molecular Formula
C16H19Cl2N5
Molecular Weight
352.26
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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