Sematilide hydrochloride
Sematilide hydrochloride is a class III antiarrhythmic agent that selectively blocks the rapid delayed rectifier potassium current (IKr) . This action prolongs the cardiac action potential duration and effective refractory period, making it a useful research tool for studying arrhythmia mechanisms in both in vitro and in vivo experimental models.
Product Specifications
CAS Number
101526-62-9
Product Name Alternative
Inhibitor, IKr, K+ current (IKr), inhibit, KcsA, current, CK1752, CK-1752, CK-1752A, CK 1752, channel, antiarrhythmic, blocker, Sematilide, Sematilide HCl, Sematilide hydrochloride, Sematilide Hydrochloride, Potassium Channel, PotassiumChannel
Field of Research
Pharmacology & Drug Discovery
Purity
99.14% (May vary between batches)
Solubility
DMSO:55 mg/mL (157.2 mM) ;10% DMSO+40% PEG300+5% Tween-80+45% Saline:1 mg/mL (2.86 mM)
Smiles
Cl.CCN (CC) CCNC (=O) c1ccc (NS (C) (=O) =O) cc1
Molecular Formula
C14H24ClN3O3S
Molecular Weight
349.87
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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