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Sematilide hydrochloride

Sematilide hydrochloride is a class III antiarrhythmic agent that selectively blocks the rapid delayed rectifier potassium current (IKr) . This action prolongs the cardiac action potential duration and effective refractory period, making it a useful research tool for studying arrhythmia mechanisms in both in vitro and in vivo experimental models.

Product Specifications

CAS Number

101526-62-9

Product Name Alternative

Inhibitor, IKr, K+ current (IKr), inhibit, KcsA, current, CK1752, CK-1752, CK-1752A, CK 1752, channel, antiarrhythmic, blocker, Sematilide, Sematilide HCl, Sematilide hydrochloride, Sematilide Hydrochloride, Potassium Channel, PotassiumChannel

Field of Research

Pharmacology & Drug Discovery

Purity

99.14% (May vary between batches)

Solubility

DMSO:55 mg/mL (157.2 mM) ;10% DMSO+40% PEG300+5% Tween-80+45% Saline:1 mg/mL (2.86 mM)

Smiles

Cl.CCN (CC) CCNC (=O) c1ccc (NS (C) (=O) =O) cc1

Molecular Formula

C14H24ClN3O3S

Molecular Weight

349.87

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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