Macozinone
Macozinone (PBTZ169) is a potent small molecule inhibitor of the Mycobacterium tuberculosis enzyme DprE1, demonstrating superior inhibitory activity compared to BTZ043. It serves as a key research tool for investigating tuberculosis drug mechanisms and has shown efficacy in both in vitro and in vivo preclinical studies.
Product Specifications
CAS Number
1377239-83-2
Product Name Alternative
Tuberculosis, antituberculosis, Bacterial, bactericidal, benzothiazinone, covalent, DprE1, inhibit, Inhibitor, Macozinone, PBTZ 169, PBTZ169, PBTZ-169
Field of Research
Infectious Disease & Virology
Purity
99.50% (May vary between batches)
Solubility
DMSO:4.57 mg/mL (10.01 mM)
Smiles
[O-][N+] (=O) c1cc (cc2c1sc (nc2=O) N1CCN (CC2CCCCC2) CC1) C (F) (F) F
Molecular Formula
C20H23F3N4O3S
Molecular Weight
456.48
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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