BMS-986176
AAK1-IN-1 is a potent and selective small molecule inhibitor of Adaptor-Associated Kinase 1, demonstrating an IC50 of 2 nM. This compound is a valuable research tool for investigating clathrin-mediated endocytosis and has been utilized in both cellular and animal models to study neurological disorders and viral entry mechanisms.
Product Specifications
CAS Number
1815613-42-3
Product Name Alternative
BMS986176, BMS-986176, BMS 986176, AP2associatedkinase1, AP2 associated kinase 1, AAK1, AAK1 (AP2 associated kinase 1), AAK-1-IN-1, AAK1 (AP2associatedkinase1), Inhibitor, neurodegenerative, LX 9211, LX9211, LX-9211, inhibit
Field of Research
Neuroscience
Purity
98.58% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween-80+45% Saline:5 mg/mL (12.97 mM) ; DMSO:220 mg/mL (570.84 mM)
Smiles
CC (C) C[C@] (C) (N) COc1ccc (nc1C (F) F) -c1ccnc (c1) C (F) F
Molecular Formula
C19H23F4N3O
Molecular Weight
385.4
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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