JAK2-IN-7
JAK2-IN-7 is a potent and selective JAK2 inhibitor with low nanomolar IC50 values against JAK2 and relevant cell lines. It demonstrates over 14-fold selectivity against related kinases and exhibits antitumor activity by inducing G0/G1 cell cycle arrest and apoptosis in vitro.
Product Specifications
CAS Number
2593402-36-7
Product Name Alternative
JAK2 IN 7, JAK2IN7, JAK-2-IN-7, JAK2-IN-7, JAK2
Field of Research
Cardiovascular Research, Cell Biology, Epigenetics & Chromatin, Signal Transduction, Stem Cell & Developmental Biology
Purity
98.71% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (10.88 mM) ; DMSO:250 mg/mL (543.96 mM)
Smiles
C (/C=C/CN (C) C) (=O) N1CC=2C (=CC (NC=3N=C (C (C) =CN3) C4=CN (C (C) C) N=C4) =CC2) CC1
Molecular Formula
C26H33N7O
Molecular Weight
459.59
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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